An integrative multi omics analysis leveraging Mendelian randomization and subsequent experimental validation prioritizes glutathione S transferase mu 5 (GSTM5) as a genomic stability related gene and a therapeutic vulnerability to PLK1 inhibition in Glutathione and Thioredoxin Antioxidant Pathways Synergize to Drive Cancer Initiation and Progression: Cancer Cell Excessive glutathione intake contributes to chemotherapy resistance in breast cancer: a propensity score matching analysis World Journal of Surgical Oncology Springer Nature Link Chemotherapy induces breast cancer stem cell enrichment through repression of glutathione S transferase Mu ScienceDirect Frontiers Glutathione responsive and exhausting metal nanomedicines for robust synergistic cancer therapy Excessive glutathione intake contributes to chemotherapy resistance in breast cancer: a propensity score matching analysis World Journal of Surgical Oncology Springer Nature Link